Transdiagnostic cognitive behavioral therapy

The Unified Protocol is an innovative, emotion-focused treatment that targets core psychological processes underlying multiple disorders, equipping clients with skills and strategies for managing symptoms across diagnoses. Our mission at the Unified Protocol Institute (UPI) is to make high-quality, evidence-based psychological treatment accessible to all. 

High Prevalence

Did you know that by age 75, approximately half of the global population can expect to develop a mental health disorder?¹

Treatment Gap

Did you know that most people who access some form of mental health support do not receive evidence-based treatment?²

Slow Adoption

Did you know that most innovations in mental health never make it into practice, and when they do, it takes an average of 17 years?³

The Unified Protocol Institute is here to change that.

Training

One treatment to address the full range of emotional disorders

Two women engaging in a conversation during a counseling session, one holding a pen and paper

Moving beyond fragmented care

As providers, we navigate complex terrain – a labyrinth of symptoms and mental health conditions can demand multiple specialized protocols for each unique client. Attempting to provide evidence-based treatment to our clients by targeting one diagnosis at a time often overburdens providers with time constraints, knowledge overload, and impending burnout. Meanwhile, our clients, who generally deal with intersecting diagnoses, may feel discouraged and struggle to commit to a treatment protocol that doesn’t align with their lived experience. The Unified Protocol’s (UP) transdiagnostic approach has emerged as a bridge across this fractured landscape.

Treatment

A unified path to healing

The Unified Protocol (UP) is the most widely used transdiagnostic treatment in the world, with a substantial body of research demonstrating its effectiveness. This transdiagnostic approach provides a single, comprehensive intervention that can address a broad range of disorders simultaneously. The UP targets the very core of mental health struggles: how people relate to their emotions, instead of a diagnostic label.

Efficient

Illustration of a woman placing a Unified Protocol book on a shelf in an organized storage area

Engaging

Illustration of a therapy session with two people seated, holding speech bubbles, and discussing the Unified Protocol

Effective

Illustration of a woman holding a Unified Protocol book with a rising graph in the background
Research

Data-driven and focused on real-world impact

We partner with researchers globally, learning from their experiences and insights as they implement the UP in their private practices, community mental health clinics, university counseling centers, intensive outpatient programs, inpatient hospitals, and other settings. We consistently incorporate these findings into our training programs as part of our mission to translate research into impact.

Bar chart showing remission rates and completion rates for the Unified Protocol: 60% remission after 12-16 weeks, 59.2% long-term remission after three years, and 87.5% treatment completion rate
¹Barlow, Farchione et al. (2017)
²Bullis, Eustis, et al. (2023)

A selection of our valued collaborators and clients

Baylor University
Cambridge Health Alliance
Emory Healthcare, Veterans Program
Fairwinds, Nantucket's Counseling Center
headspace
Home Base, Veteran and Family Care
Mass General Brigham
The Renfrew Center, First in Eating Disorders
SilverCloud, Part of amwell
U.S. Air Force
U.S. Department of Veterans Affairs

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